To what extent do the muscles and tendons influence metabolic cost and exercise tolerance in the hypermobile Ehlers-Danlos Syndrome and Hypermobility Spectrum Disorders?
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Issue Date
2025-11-17
Editor
Authors
Sheehan, Dawson S.
Oliemans, Jason P.
Golden, Donald W.
Walls, Kalinda D.
Bennett, Eric C.
Skaper, Spencer J.
Asmussen, Michael J.
Manocha, Ranita H.K.
Fletcher, Jared R.
Subject
Abstract
Individuals with hypermobile Ehlers-Danlos Syndrome (hEDS) and Hypermobility Spectrum Disorders (HSD) often experience chronic pain, muscle fatigue, and exercise intolerance, potentially due to altered muscle-tendon mechanics. This study investigated the influence of Achilles tendon (AT) compliance and plantar flexor muscle function on the metabolic cost of walking in individuals with and without HSD/hEDS.
Description
This article was originally published as: Sheehan, D.S., Oliemans, J.P., Golden, D.W., Walls, K.D., Bennett, E.C., Skaper, S.J., Asmussen, M.J., Manocha, R.H.K., & Fletcher, J.R. (2025). To what extent do the muscles and tendons influence metabolic cost and exercise tolerance in the hypermobile Ehlers-Danlos Syndrome and Hypermobility Spectrum Disorders?. Clinical Biomechanics, 131, Article 106695. https://doi.org/10.1016/j.clinbiomech.2025.106695