VIURRSpace

The Libraries of Royal Roads University and Vancouver Island University collaboratively offer VIURRSpace to digitally preserve and showcase selected scholarly and creative works of the universities, together with special collections that represent the unique character of the region.

Recent Submissions

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    Let’s not forget the role of environmental psychology in our quest for healthier cities
    (Routledge, 2022-11-14) McCunn, Lindsay J.; Arnett, Hannah
    Leading editorial for Cities & Health, Volume 6, Issue 6: Planning for people and health - environmental psychology in the city.
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    PAMAM-functionalized paper as a new substrate for the paper spray mass spectrometry measurement of proteins
    (ACS Publications, 2023-04-28) Pereira, Igor; Monaghan, Joseph; Abruzzi, Lucas R.; Gill, Chris G.
    Paper surface functionalization with polyamidoamine (PAMAM) dendrimers has been developed for increased sensitivity analysis of proteins by paper spray mass spectrometry (PS-MS). PAMAM is a branched polymeric compound with an ethylenediamine core linked to repeating PAMAM units that generates an outer surface rich in primary amines. These positively charged amine groups can interact electrostatically with negatively charged residues (e.g., aspartate, glutamate) on the protein surface. PAMAM inner amide moieties can also promote hydrogen bonding with protein surface oxygens, making PAMAM a useful material for protein extraction. PAMAM-functionalized PS-MS paper strips were used to extract proteins from biofluids, dipped in acetonitrile to remove unbound constituents, dried, and then measured with PS-MS. The use of this strategy was optimized and compared with unmodified paper strips. PAMAM-functionalized paper substrates provided sixfold greater sensitivity for albumin, 11-fold for hemoglobin, sevenfold for insulin, and twofold for lysozyme. The analytical performance of the functionalized paper substrate was evaluated through the analysis of albumin in urine, achieving linearity with R2 > 0.99, LOD of 1.1 μg mL–1, LOQ of 3.8 μg mL–1, precision better than 10%, and relative recovery 70–83%. The method was applied to quantify urinary albumin from nine anonymous patient samples (concentrations ranged from 6.5 to 77.4 μg mL–1), illustrating its potential for the diagnosis of microalbuminuria. These data demonstrate the utility of paper modification with the PAMAM dendrimer for sensitive PS-MS analysis of proteins, opening a path for further applications in clinical diagnosis through the analysis of disease-related proteins.
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    Beyond the underground: Planning strategies to improve music culture and nightlife in Nanaimo
    (Electronic version published by Vancouver Island University, 2024-04) McCulloch, Aidan; Chase, Lindsay
    As an emerging topic in planning practice, this research explores the perspectives of those involved with the facilitation of nightlife perceive the City of Nanaimo, British Columbia, and explores how current policy may have shaped the nightlife landscape. By exploring academic perspectives of normative concepts which have facilitated positive governing attitudes of nightlife, this research applies the theoretical framework of advocacy planning to conceptualize how the City of Nanaimo and the planning profession should understand when considering policy support for nightlife activity.
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    A Systems Thinking Approach to Examine Local Food Systems Planning Through a Climate-Biodiversity-Health Lens: A Comox Valley Case Study
    (2024) Issac, Jofri; Newell, Robert
    Food systems are highly vulnerable to the effects of anthropogenic climate change and environmental degradation. At the same time, food systems contribute significantly to the production of greenhouse gases that drive climate change and negatively impact ecosystems. Such a vicious cycle of cause and effect demands a transition to sustainable food systems, and this is best done through integrated planning and policy perspectives that tackle interconnected socioeconomic and environmental concerns and goals. This research applies systems thinking to map relationships among food systems planning and other sustainability priorities, namely those related to climate, biodiversity, and health. The study engaged stakeholders in the Comox Valley region, British Columbia, to develop a causal loop diagram, which was subsequently analyzed using the Girvan-Newman community detection algorithm to identify closely connected nodes or 'clusters'. The results of this work provide a comprehensive understanding of how local food systems' challenges and opportunities connect and integrate with other local and regional sustainability objectives. The research identified 123 systems nodes, which were organized into five categories: food, climate, biodiversity, health, and governance. The community detection method was applied to reveal 15 clusters among these nodes. The methodology employed in this research, integrating the development of a causal loop diagram, and applying community detection, is novel and contributes to the growing body of literature advocating for an integrated planning approach to address the complex challenges facing local and regional food systems.
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    Cocreating Empowered Leadership Outcomes with Former Youth in Care in British Columbia
    (2024) Sort, Kaeli, Rose; Holmes, Shawn, Y
    Former youth in care (FYiC) face unique challenges and disproportionate rates of suicide, trafficking, homelessness, and poor employment outcomes. While the British Columbian government recently expanded support to FYiC to 27 years of age, this research shows FYiC participants ages 30–45 years continue to suffer significant and chronic traumas. Using community-based participatory action research, this thesis explored the inquiry question: How might we learn from the experiences of FYiC to influence equitable policies in leadership? Participants took part in a survey, interviews, and a group discussion. The recommendations are to involve FYiC in the decisions that affect them, create a list of trauma-informed leadership practices to enhance decision making and risk mitigation, leverage and celebrate the talents of FYiC, provide resources that empower FYiC to advance their personal circumstances, and invest in feedback mechanisms to support the implementation of policies that better meet FYiC’s unique needs, goals, and circumstances.

Communities in VIURRSpace

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Now showing 1 - 2 of 2
  • RRU
    Royal Roads University DSpace
  • VIUSpace
    The Institutional Repository of Vancouver Island University